Gut Health
The gut is the foundation of whole-body health — from immunity to mood. Here is what the evidence says about healing and maintaining it.
This page is for educational purposes only and does not replace medical advice. If you have a diagnosed gut condition (IBS, IBD, Crohn's, coeliac), work with your gastroenterologist.
Key nutrients for gut health
The compounds with the strongest evidence for microbiome support and gut lining repair.
Lactobacillus & Bifidobacterium
Grade A10–50 billion CFU/day
The most-studied probiotic genera. Reduce IBS symptoms, antibiotic-associated diarrhoea, and improve microbiome diversity. Strain matters — L. rhamnosus GG and B. longum BB536 have the strongest evidence.
Prebiotic fibre (inulin/FOS)
Grade A5–10g/day
Feeds beneficial bacteria, increases Bifidobacterium counts, and improves stool consistency. Found in chicory, garlic, onion, leeks, and Jerusalem artichoke.
L-Glutamine
Grade B5–10g/day
Primary fuel for enterocytes (gut lining cells). Reduces intestinal permeability ("leaky gut") in RCTs. Particularly useful after illness, antibiotics, or high-stress periods.
Zinc carnosine
Grade B75mg/day
Stabilises the gut lining and reduces mucosal inflammation. Used clinically for gastric ulcers and leaky gut. Better absorbed than standard zinc.
Butyrate (or tributyrin)
Grade B300–600mg/day
Short-chain fatty acid that fuels colonocytes, reduces gut inflammation, and supports the gut-brain axis. Produced naturally by fermenting fibre — or supplemented directly.
Saccharomyces boulardii
Grade A250–500mg/day
A probiotic yeast with strong evidence for preventing and treating diarrhoea, including traveller's diarrhoea and C. difficile recurrence. Survives antibiotics.
6 natural strategies with strong evidence
Ranked by effect size and quality of evidence.
Eat 30+ different plant foods per week
The American Gut Project found that people eating 30+ plant varieties per week had significantly more diverse microbiomes than those eating 10 or fewer. Diversity is the single strongest predictor of gut health.
Eat fermented foods daily
A Stanford RCT (2021) found that a high-fermented-food diet increased microbiome diversity and reduced inflammatory markers more than a high-fibre diet alone. Yogurt, kefir, kimchi, sauerkraut, and miso are the most evidence-backed sources.
Minimise ultra-processed foods
Ultra-processed foods (emulsifiers, artificial sweeteners, refined carbohydrates) reduce microbiome diversity, increase intestinal permeability, and promote dysbiosis. Polysorbate 80 and carboxymethylcellulose have direct evidence for gut lining disruption.
Manage stress actively
The gut-brain axis is bidirectional — chronic stress alters gut motility, increases permeability, and shifts the microbiome toward dysbiosis. Mindfulness-based stress reduction (MBSR) improves IBS symptoms in RCTs.
Exercise regularly
Regular aerobic exercise increases microbiome diversity and short-chain fatty acid production independently of diet. Even 150 min/week of moderate activity produces measurable microbiome improvements.
Use antibiotics only when necessary
A single course of broad-spectrum antibiotics can reduce microbiome diversity by 25–50%, with some species not recovering for 6–12 months. When antibiotics are necessary, take S. boulardii concurrently and follow with a probiotic course.
Best foods for gut health
Whole foods with the strongest evidence for microbiome diversity and gut lining integrity.
Gut health articles
Evidence-reviewed articles on the microbiome, probiotics, and digestive health.
Probiotics & Fermented Foods: What the Evidence Shows
The strains with the strongest evidence for gut health, immunity, and mood — and the foods that deliver them.
Kids' Gut Health & Probiotics
How the infant and childhood microbiome shapes immunity, behaviour, and long-term health.
Whole Foods Nutrition Guide
A practical guide to eating for microbiome diversity and gut lining integrity.
Ready to heal your gut?
The Gut Health Plan gives you a structured 7-day protocol with nutrition, probiotic, and lifestyle guidance.
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